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DISCOVER Trial Factsheet

7 July 2022

This factsheet provides details on the DISCOVER trial to assess whether F/TAF (trade name Descovy) is as safe and effective as an oral daily HIV pre-exposure prophylaxis (PrEP) product.

Topic(s): Community/Advocacy, Research

Product(s): F/TAF, Oral PrEP

Population(s): Gay and Bisexual Men Who Have Sex With Men, Trans Women

Region(s): North America

Countries: United States

Source(s): AVAC

Type: External Link

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Featured Resources

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Differentiated HIV Services for Transgender People in Four South African Districts: Population characteristics and HIV care cascade

This article from the Journal of the International AIDS Society describes a differentiated service delivery model across four South African sites and transgender individuals who access these services. It assesses whether hormone therapy is associated with continued use of PrEP and viral load suppression.
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Travestis, Transgender Women and Young MSM are at High Risk for PrEP Early Loss to Follow-up in Rio de Janeiro, Brazil

This article from the Brazilian Journal of Infectious Diseases identifies factors associated with PrEP early loss to follow-up among gay, bisexual and other men who have sex with men, travestis, and transgender women in Rio de Janeiro, Brazil.
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PrEP Risk Perception and Adherence among Men who have Sex with Men: A prospective cohort study based on growth mixture model

This study from BMC Infectious Diseases explores PrEP risk perception among gay and bisexual men who have sex with men in western China and its impact on PrEP adherence.
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A Capacity-Strengthening Intervention to Support HIV Pre-exposure Prophylaxis (PrEP) Awareness-Building and Promotion by Frontline Harm Reduction Workers in Baltimore, Maryland: A mixed methods evaluation

This article from AIDS and Behavior describes the results of an intervention to increase knowledge and awareness of PrEP amongst people who inject drugs in Baltimore, Maryland, USA.

Southern African HIV Clinicians Society PrEP Training Curriculum

This training curriculum was developed by the Southern African HIV Clinicians Society to support implementers rolling out PrEP. Module 1a: A basic overview and introduction to PrEP Module 1b: Evidence of PrEP effectiveness Module 2: Providing PrEP- the basics Module 3a: Overview of key populations Module 3b: Gay and bisexual men who have sex with…
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Costs and Cost-Effectiveness of Biomedical, Non-Surgical HIV Prevention Interventions: A systematic literature review

This article from PharmacoEconomics synthesizes findings on cost and cost-effectivness of different biomedical HIV prevention options and identifies remaining knowledge gaps to suggest future research priorities.
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Barriers to PrEP Uptake among Black Female Adolescents and Emerging Adults

This article from Preventative Medicine Reports examines the characteristics of age, race, gender, history, and medical mistrust as barriers to PrEP uptake among Black female adolescents and emerging adults between the ages of 13–24 years in Chicago, Illinois, USA.
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Guidelines on Use of ARV Drugs for Treating and Preventing HIV Infections in Kenya (2018)

These guidelines from Kenya’s National AIDS & STI Control Program (NASCOP) cover HIV testing services and linkage to prevention and treatment; initial evaluation and follow up of People Living with HIV (PLHIV); standard package of care for PLHIV; adherence preparation monitoring and support; antiretroviral therapy in infants, children, adolescents and adults; prevention of mother to…
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Rapid Assessment on Access to PrEP in EU/EEA Countries

This report by AIDS Action Europe summarizes the results of a survey of member organizations and partners based in EU Member States on various aspects of availability, accessibility, affordability, and acceptability of PrEP in their national context. In addition to the main findings, it includes country profiles and recommendations for the European Union and its…
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The Effect of Pre-exposure Prophylaxis (PrEP) on Negotiating Casual Sex between Gay Men: Disclosure, assumptions, and communication

This article from Sexual Health explores the disclosure of PrEP use, HIV status and communication with sex partners by HIV-negative gay men in Sydney, Australia.