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The PrEPWatch Resource Database offers a wide range of material on the status of PrEP as an option for biomedical HIV prevention around the world. Search this database to find step-by-step guidance for rolling out PrEP, summaries of the research to date on safety, efficacy and implementation, tools to assist planning and roll out, country updates on PrEP policy and access, and lessons learned from those efforts.

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7 July 2022

Microbicide Trials Network-043 – B-PROTECTED Study

Microbicide Trials Network-043, or B-PROTECTED, is a Phase IIIb open-label study that evaluated the safety and acceptability of the monthly dapivirine ring and daily oral PrEP in women who are breastfeeding, a time of heightened vulnerability for acquiring HIV.

Research

External Link
7 July 2022

Use of the Dapivirine vaginal ring and effect on cervical cytology abnormalities

This study aims to determine if the dapivirine vaginal ring and the ring device alone (flexible silicone matrix polymer) was associated with the development of cervical cytology abnormalities.

Research, Service Delivery

External Link
7 July 2022

HPTN 084

The HIV Prevention Trials Network (HPTN) hosted a community webinar to discuss the primary results of HPTN 084, a randomized, double-blind controlled trial designed to evaluate the efficacy and safety of long-acting injectable cabotegravir (CAB LA) to prevent the sexual acquisition of HIV in cisgender women in sub-Saharan Africa.

Research

External Link
7 July 2022

HOPE Protocol Team Meeting Lessons Learned from PrEP Rollout for the Dapivirine Ring

This presentation outlines lessons from oral PrEP demonstration projects that could be applied to the rollout of the dapivirine vaginal ring as well as plans for ring introduction.

Research

Document
7 July 2022

Health Care Providers’ Attitudes toward and Experiences Delivering Oral PrEP to Adolescent Girls and Young Women in Kenya, South Africa, and Zimbabwe

This article describes the results of a cross-sectional qualitative study, interviewing providers at public, private, and nongovernmental health facilities in Kenya, South Africa, and Zimbabwe offering PrEP to explore providers’ attitudes toward and experiences delivering PrEP to AGYW.

Research, Service Delivery

External Link
7 July 2022

Health care providers’ attitudes toward and experiences delivering oral PrEP to adolescent girls and young women: Zimbabwe technical brief

This technical brief describes the results of a cross-sectional qualitative study, interviewing providers at public, private, and nongovernmental health facilities in Zimbabwe offering PrEP to explore providers’ attitudes toward and experiences delivering PrEP to AGYW.

Research, Service Delivery

Document
7 July 2022

What Young Women Want

This letter comes from a group of young African women and reflects their HIV prevention research priorities. It was submitted to the National Institutes of Health’s (NIH) Division of AIDS (DAIDS) during the open-comment period concerning the structure and agenda for its next funding cycle (2021-2027).

Community/Advocacy

External Link
7 July 2022

Results of open-label study of a vaginal ring for HIV prevention suggest women are interested in and willing to use it

This article from the Microbicide Trials Network shares the results of an open-label study of a vaginal ring for HIV prevention

Community/Advocacy, Demand Creation/Marketing, Research

External Link
7 July 2022

Adherence to the Dapivirine vaginal ring and oral PrEP among adolescent girls and young women in Africa: interim results from the REACH study

Adolescent girls and young women (AGYW) account for most new HIV infections in sub-Saharan Africa. WHO has endorsed oral PrEP and dapivirine vaginal ring (ring) for women at substantial risk of HIV infection. However, adherence to both products was lower among younger women in randomized placebo-controlled trials. The authors of this article assessed interim safety,…

Research

External Link
7 July 2022

Microbicide Trials Network-042 – DELIVER Study

Microbicide Trials Network-042/DELIVER is a Phase IIIb open-label study designed to evaluate the safety and acceptability of the monthly dapivirine vaginal ring and oral PrEP in pregnant women.

Research

External Link